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Dietary Natural Lutein and Its Impact on Hepatic Autoimmunity in Long COVID: A Clinical Case Study

Anthony M Kyriakopoulos Laboratory of Molecular Biology and Immunology, Department of Pharmacy, University of Patras, Rio-Patras, 26500, Greece and Department of Research and Development, Nasco AD Biotechnology Laboratory, Piraeus, Greece. Peter A McCullough McCullough Foundation, Dallas, TX, USA. Stephanie Seneff * Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge MA, 02139, USA. Abstract…

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Do Methylation Pathways Carry Microbially Derived Deuterium-Depleted Methyl Groups to Support Mitochondrial Health?

August 2025 DOI:10.20944/preprints202509.0145.v1 License CC BY 4.0 Authors: Stephanie Seneff Massachusetts Institute of Technology Greg Nigh Greg Nigh LLC Anthony Kyriakopoulos Nasco AD Biotech Lab Abstract One-carbon metabolism (also known as the methylation pathway) is a fundamental biochemical process involving the transfer of methyl groups from one molecule to another, to carry out many cellular…

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Clinical rationale for dietary lutein supplementation in post COVID-19 and mRNA vaccine injury syndromes

Abstract Lutein, a plant-derived xanthophyl-carotenoid, is an exceptional antioxidant and anti-inflammatory constituent found in food. High dietary intake of lutein is beneficial against eye disease, improves cardiometabolic health, protects from neurodegenerative diseases, and is beneficial for liver, kidney, and respiratory health. Lutein protects against oxidative and nitrosative stress, both of which play a major role…

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Dietary Lutein and Cognitive Function in Adults: A Meta-Analysis of Randomized Controlled Trials

Dietary Lutein and Cognitive Function in Adults: A Meta-Analysis of Randomized Controlled Trials Jeffrey Li 1, El-Sayed M Abdel-Aal 2 PMID: 34641336 PMCID: PMC8510423 DOI: 10.3390/molecules26195794 Free PMC article Abstract Emerging literature suggests that dietary lutein may have important functions in cognitive health, but there is not enough data to substantiate its effects in human cognition. The current study was intended…

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Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression

Dietary lutein reduces ultraviolet radiation-induced inflammation and immunosuppression Erica H Lee 1, Dorothea Faulhaber, Kerry M Hanson, Wanhong Ding, Sara Peters, Sreedevi Kodali, Richard D Granstein PMID: 15009738 DOI: 10.1046/j.0022-202X.2004.22227.x J Invest Dermatol. 2005 May;124(5):1092 Abstract Ultraviolet radiation (UVR) promotes skin cancer development by mutagenic, immunosuppressive, and oxidative-stress-inducing mechanisms; however, certain antioxidants may counteract and prevent UVR-induced photodamage. Lutein is a xanthophyll carotenoid with…

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Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial

Overall skin tone and skin-lightening-improving effects with oral supplementation of lutein and zeaxanthin isomers: a double-blind, placebo-controlled clinical trial Vijaya Juturu,1 James P Bowman,2 and Jayant Deshpande1 Author information Copyright and License information Disclaimer Go to: Abstract Purpose Carotenoids, especially lutein and zeaxanthin isomers (L/Zi), filter blue light and protect skin from environmental factors including high-energy sources. These carotenoids may…

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Antifungal Activity of Phenolic and Polyphenolic Compounds from Different Matrices of Vitis vinifera L. against Human Pathogens

Molecules. 2020 Aug; 25(16): 3748. Published online 2020 Aug 17. doi: 10.3390/molecules25163748 PMCID: PMC7464220 PMID: 32824589 Antifungal Activity of Phenolic and Polyphenolic Compounds from Different Matrices of Vitis vinifera L. against Human Pathogens Giovanna Simonetti,† Elisa Brasili,† and Gabriella Pasqua* Paola Di Donato, Academic Editor and Brigida Silvestri, Academic Editor Author information Article notes Copyright and License information Disclaimer Abstract Phenolic compounds, the most widely distributed class of natural products in…

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Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases

Antioxidants (Basel). 2019 Dec; 8(12): 578. Published online 2019 Nov 22. doi: 10.3390/antiox8120578 PMCID: PMC6943788 PMID: 31766676 Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases Chiara Nediani,1,* Jessica Ruzzolini,1 Annalisa Romani,2 and Lido Calorini1,3 Author information Article notes Copyright and License information Disclaimer Go to: Abstract Growing scientific literature data suggest that the intake of natural bioactive compounds plays…

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Oleuropein: A natural antioxidant molecule in the treatment of metabolic syndrome

Oleuropein: A natural antioxidant molecule in the treatment of metabolic syndrome Javed Ahamad1, Ibrahim Toufeeq1, Mohammad Ahmed Khan2, Muath Sh Mohammed Ameen1, Esra T Anwer1, Subha Uthirapathy1, Showkat R Mir3, Javed Ahmad4 Affiliations 1Faculty of Pharmacy, Tishk International University, Erbil, Iraq. 2Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. 3Department of Pharmacognosy, School of Pharmaceutical Education…

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Swift Cure of a Chronic Wound Infected With Multiresistant Staphylococcus aureus in an Elderly Patient With Stage 5 Renal Disease

Anthony M Kyriakopoulos 1, Eirini Grapsa 2, Janusz Marcinkiewicz 3, Markus Nagl 4 Affiliations collapse Affiliations 11 Nasco AD Biotechnology Laboratory, Piraeus, Greece. 22 Areteio Medical Hospital, Medical School of the University of Athens, Athens, Greece. 33 Jagiellonian University Medical College, Krakow, Poland. 44 Medical University of Innsbruck, Innsbruck, Austria. PMID: 30929522 DOI: 10.1177/1534734619834746 Abstract We present a case of a 91-year-old female with stage…